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Mike Derheim
 
February 18, 2025 | All about wine! | Mike Derheim

The Truth about Sulphates in winemaking: do they really cause headaches?

When it comes to wine, few topics spark as much debate as the use of sulphates (or sulfites, as they’re often called). For some, sulphates are a necessary part of winemaking, ensuring stability and preserving flavor. For others, they’re the alleged culprits behind those dreaded wine-induced headaches. But what’s the real story? Are sulphates truly to blame, or is this just a widespread myth? Let’s dive into the science and separate fact from fiction.

What Are Sulphates, and Why Are They Used in Winemaking?

Sulphates, or sulfur dioxide (SO₂), are compounds used in winemaking as preservatives and antioxidants. They play a crucial role in protecting wine from oxidation and microbial spoilage. Without sulphates, wine would be far more susceptible to turning into vinegar or developing off-flavors. Even in ancient times, winemakers used sulfur-based compounds to preserve their wines, though modern techniques have refined the process.

Sulphates are added at various stages of winemaking:

  • During fermentation: To control wild yeast and bacteria.
  • After fermentation: To prevent oxidation and maintain freshness.
  • Before bottling: To ensure the wine remains stable during storage and transport.

Interestingly, sulphates are also a natural byproduct of fermentation, meaning even wines labeled as "no added sulphates" still contain trace amounts.

The Headache Debate: Are Sulphates Really to Blame?

One of the most persistent claims about sulphates is that they cause headaches. This belief has led many wine drinkers to seek out low-sulphate or sulphate-free wines. But is there any scientific basis for this?

The Science Says: Probably Not

Research has shown that sulphates are unlikely to be the primary cause of wine-related headaches. In fact, only about 1% of the population is truly sensitive to sulphates, and even then, the symptoms are typically respiratory (like asthma) rather than headaches. The FDA estimates that less than 0.1% of people have a severe sulphite allergy, which is far lower than the number of people who blame sulphates for their wine headaches.

So, if sulphates aren’t the main culprit, what is? There are several other potential causes of wine-induced headaches:

  • Histamines: Red wine, in particular, contains histamines, which can cause headaches in sensitive individuals. Histamines are naturally occurring compounds that dilate blood vessels, potentially leading to discomfort.
  • Tannins: These compounds, found in the skins, seeds, and stems of grapes, are more prevalent in red wines. Tannins can trigger headaches in some people by releasing serotonin, a neurotransmitter that can cause blood vessels to constrict.
  • Alcohol Content: Higher alcohol levels can lead to dehydration, a common cause of headaches. Alcohol also dilates blood vessels, which can contribute to discomfort.
  • Tyramine: This compound, found in aged and fermented foods (including wine), has been linked to headaches in some individuals.
  • Sugar Levels: Sweet wines or those with residual sugar can cause blood sugar spikes and crashes, which may lead to headaches.
Why Do People Blame Sulphates?

If sulphates aren’t the main cause of headaches, why do so many people point the finger at them? There are a few reasons:

  • Misinformation: The idea that sulphates cause headaches has been widely circulated, often without scientific backing.
  • Labeling: Wines with "no added sulphates" are marketed as healthier or more natural, reinforcing the perception that sulphates are harmful.
  • Placebo Effect: If someone believes sulphates cause headaches, they may experience symptoms simply because they expect to.
Should You Avoid Sulphates in Wine?

For most people, there’s no need to avoid sulphates in wine. They’re a vital tool for winemakers, ensuring that the wine you enjoy is fresh, stable, and free from spoilage. However, if you suspect you’re sensitive to sulphates or other compounds in wine, here are a few tips:

  • Experiment: Try wines with lower sulphate levels or sulphate-free options to see if it makes a difference.
  • Stay Hydrated: Drinking water alongside wine can help mitigate dehydration-related headaches.
  • Choose Wisely: Opt for wines with lower alcohol content or fewer tannins if those are potential triggers for you.
The Bottom Line

Sulphates are an essential part of winemaking, and the evidence suggests they’re not the primary cause of wine headaches for most people. While individual sensitivities vary, factors like histamines, tannins, and alcohol content are more likely to blame. So, the next time you enjoy a glass of wine, you can raise your glass to sulphates—without worrying too much about that headache myth. Cheers! 🍷

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